Maduromycosis, also known as eumycetoma is caused by various fungi (e.g. madurella mycetomi) or actinomycetes (e.g. nocardia brasiliensis) which usually affects the feet.

Initially a nodule, or abscess over months to years progresses to a chronic infection with the formation of granulomatous nodules drained by sinuses connecting with the skin. Superimposed bacterial infection may result in larger open ulcers.

These changes eventually lead to deformity. The changes on imaging are remarkable with the bones being destroyed and remodeled.

It is presumably named after Madura Island off the east coast of Java.


Current Medical Diagnosis & Treatment 2007, McGraw-Hill

Credit: Dr Frank Gaillard